Current Applications using Adult Stem Cells

 
Stem Cell Disorders
• Aplastic Anemia (Severe)
• Fanconi Anemia
• Paroxysmal Nocturnal Hemoglobinuria (PNH)

Acute Leukemias • Acute Lymphoblastic Leukemia (ALL)
• Acute Myelogenous Leukemia (AML)
• Acute Biphenotypic Leukemia
• Acute Undifferentiated Leukemia

Chronic Leukemias
• Chronic Myelogenous Leukemia (CML)
• Chronic Lymphocytic Leukemia (CLL)
• Juvenile Chronic Myelogenous Leukemia (JCML)
• Juvenile Myelomonocytic Leukemia (JMML)

Myeloproliferative Disorders
• Acute Myelofibrosis
• Agnogenic Myeloid Metaplasia (myelofibrosis)
• Polycythemia Vera
• Essential Thrombocythemia

Myelodysplastic Syndromes
• Refractory Anemia (RA)
• Refractory Anemia with Ringed Sideroblasts (RARS)
• Refractory Anemia with Excess Blasts (RAEB)
• Refractory Anemia with Excess Blasts in Transformation (RAEB-T)
• Chronic Myelomonocytic Leukemia (CMML)

Lymphoproliferative Disorders
• Non-Hodgkin's Lymphoma
• Hodgkin's Disease
• Prolymphocytic Leukemia

Inherited Erythrocyte Abnormalities
• Beta Thalassemia Major
• Pure Red Cell Aplasia
• Sickle Cell Disease

Liposomal Storage Diseases
• Mucopolysaccharidoses (MPS)
• Hurler Syndrome (MPS-IH)
• Scheie Syndrome (MPS-IS)
• Hunter's Syndrome (MPS-II)
• Sanfilippo Syndrome (MPS-III)
• Morquio Syndrome (MPS-IV)
• Maroteaux-Lamy Syndrome (MPS-VI)
• Sly Syndrome, Beta-Glucuronidase Deficiency (MPS-VII)
• Adrenoleukodystrophy
• Mucolipidosis II (I-cell Disease)
• Krabbe Disease
• Gaucher's Disease
• Niemann-Pick Disease
• Wolman Disease
• Metachromatic Leukodystrophy

Histiocytic Disorders
• Familial Erythrophagocytic Lymphohistiocytosis
• Histiocytosis-X
• Hemophagocytosis

Phagocyte Disorders
• Chediak-Higashi Syndrome
• Chronic Granulomatous Disease
• Neutrophil Actin Deficiency
• Reticular Dysgenesis

Congenital Immune System Disorders
• Ataxia-Telangiectasia
• Kostmann Syndrome
• Leukocyte Adhesion Deficiency
• DiGeorge Syndrome
• Bare Lymphocyte Syndrome
• Omenn's Syndrome
• Severe Combined Immunodeficiency (SCID)
• SCID with Adenosine Deaminase Deficiency
• Absence of T & B Cells SCID
• Absence of T Cells, Normal B Cell SCID
• Common Variable Immunodeficiency
• Wiskott-Aldrich Syndrome
• X-Linked Lymphoproliferative Disorder

Inherited Platelet Abnormalities
• Amegakaryocytosis / Congenital Thrombocytopenia

Plasma Cell Disorders
• Multiple Myeloma
• Plasma Cell Leukemia
• Waldenstrom's Macroglobulinemia

Other Inherited Disorders
• Lesch-Nyhan Syndrome
• Cartilage-Hair Hypoplasia
• Glanzmann Thrombasthenia
• Osteopetrosis

Other Malignancies
• Breast Cancer
• Ewing Sarcoma
• Neuroblastoma
• Renal Cell Carcinoma